研究業績 2018年

臨床をすべての中心として、ひとつひとつの症例を大切にしながら、日々研究に教育に勤しんでいます。その過程で、教室メンバーが関わってきた論文をご紹介します。

1. Inuzuka T, Ueda Y, Arasawa S, Takeda H, Matsumoto T, Osaki Y, Uemoto S, Seno H, Marusawa H.

Expansion of viral variants associated with immune escape and impaired virion secretion in patients with HBV reactivation after resolved infection.
Sci Rep. 2018 Dec 24;8(1):18070.

2. Nakanishi Y, Duran A, L'Hermitte A, Shelton PM, Nakanishi N, Reina-Campos M, Huang J, Soldevila F, Baaten BJG, Tauriello DVF, Castilla EA, Bhangoo MS, Bao F, Sigal D, Diaz-Meco MT, Moscat J.

Simultaneous Loss of Both Atypical Protein Kinase C Genes in the Intestinal Epithelium Drives Serrated Intestinal Cancer by Impairing Immunosurveillance.
Immunity. 2018 Dec 18;49(6):1132-1147.

3. Nikaido M, Miyamoto S, Setoyama T, Yamauchi Y, Seno H.

Twelve-year natural history of early esophagogastric junction cancer in an extremely old patient.
Geriatr Gerontol Int. 2018 Dec;18(12):1648-1649.

4. Tsuchido Y, Nagao M, Matsuura M, Nakano S, Yamamoto M, Matsumura Y, Seno H, Ichiyama S.

Real-time quantitative PCR analysis of endoscopic biopsies for diagnosing CMV gastrointestinal disease in non-HIV immunocompromised patients: a diagnostic accuracy study.
Eur J Clin Microbiol Infect Dis. 2018 Dec;37(12):2389-2396.

5. Yamaga Y, Fukuda A, Nakanishi Y, Chiba T, Seno H.

Gene expression profile of Dclk1+ cells in intestinal tumors.
Dig Liver Dis. 2018 Dec;50(12):1353-1361.

6. Eso Y, Furuta A, Takai A, Takahashi K, Ueda Y, Marusawa H, Seno H.

Ultrasound-guided microfoam sclerotherapy with polidocanol for symptomatic giant hepatic cyst - Initial experience.
Hepatol Res. 2018 Nov;48(12):1055-1063.

7. Yao S, Taura K, Okuda Y, Kodama Y, Uza N, Gouda N, Minamiguchi S, Okajima H, Kaido T, Uemoto S.

Effect of mapping biopsy on surgical management of cholangiocarcinoma.
J Surg Oncol. 2018 Nov;118(6):997-1005.

8. Mizuguchi A, Takai A, Shimizu T, Matsumoto T, Kumagai K, Miyamoto S, Seno H, Marusawa H.

Genetic features of multicentric/multifocal intramucosal gastric carcinoma.
Int J Cancer. 2018 Oct 15;143(8):1923-1934.

9. Yoshikawa T, Ohana M, Fukuda A.

An Infected Aortic Aneurysm After Successful Treatment of Nontyphoidal Salmonella Gastroenteritis.
Clin Gastroenterol Hepatol. 2018 Oct;16(10):e106-e107.

10. Nakamura S, Imaeda H, Nishikawa H, Iimuro M, Matsuura M, Oka H, Oku J, Miyazaki T, Honda H, Watanabe K, Nakase H, Andoh A.

Usefulness of fecal calprotectin by monoclonal antibody testing in adult Japanese with inflammatory bowel diseases: a prospective multicenter study.
Intest Res. 2018 Oct;16(4):554-562.

11. Shinzaki S, Fujii T, Bamba S, Ogawa M, Kobayashi T, Oshita M, Tanaka H, Ozeki K, Takahashi S, Kitamoto H, Kani K, NanjoS, Sugaya T, Sakakibara Y, Inokuchi T, Kakimoto K, Yamada A, Yasuhara H, Yokoyama Y, Yoshino T, Matsui A, Nakamura M, Tomizawa T, Sakemi R, Kamata N, Hibi T.

Seven days triple therapy for eradication of Helicobacter pylori does not alter the disease activity of patients with inflammatory bowel disease.
Intest Res. 2018 Oct;16(4):609-618.

12. Nishikawa Y, Uza N, Yamauchi Y, Fukuda A, Ueda Y, Kodama Y, Seno H.

Successful endoscopic removal of fractured guidewire fragments from a peripheral bile duct using a biliary stent delivery system and biopsy forceps.
Endoscopy. 2018 Oct;50(10):E279-E280.

13. Sogabe Y, Yamamoto S, Kodama Y.

Unusual cause of a pancreatic mass.
Gastrointest Endosc. 2018 Oct;88(4):770-771.

14. Sogabe Y, Seno H, Yamamoto T, Yamada Y.

Unveiling epigenetic regulation in cancer, aging and rejuvenation with in vivo reprogramming technology.
Cancer Sci. 2018 Sep;109(9):2641-2650.

15. Eso Y, Takai A, Taura K, Takahashi K, Ueda Y, Marusawa H, Seno H.

Association of Mac-2-binding protein glycosylation isomer level with nutritional status in chronic liver disease.
J Gastroenterol Hepatol. 2018 Sep;33(9):1649-1658.

16. Muta Y, Matsuda M, Imajo M.

Dynamic ERK signaling regulation in intestinal tumorigenesis.
Mol Cell Oncol. 2018 Sep 11;5(5):e1506684.

17. Shiokawa M, Kodama Y, Sekiguchi K, Kuwada T, Tomono T, Kuriyama K, Yamazaki H, Morita T, Marui S, Sogabe Y, Kakiuchi N, Matsumori T, Mima A, Nishikawa Y, Ueda T, Tsuda M, Yamauchi Y, Sakuma Y, Maruno T, Uza N, Tsuruyama T, Mimori T, Seno H, Chiba T.

Laminin 511 is a target antigen in autoimmune pancreatitis.
Sci Transl Med. 2018 Aug 8;10(453).

18. Tsuda M, Fukuda A, Roy N, Hiramatsu Y, Leonhardt L, Kakiuchi N, Hoyer K, Ogawa S, Goto N, Ikuta K, Kimura Y, Matsumoto Y, Takada Y, Yoshioka T, Maruno T, Yamaga Y, Kim GE, Akiyama H, Ogawa S, Wright CV, Saur D, Takaori K, Uemoto S, Hebrok M, Chiba T, Seno H.

The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis.
J Clin Invest. 2018 Aug 1;128(8):3475-3489.

19. Eso Y, Uza N, Shirakawa K, Sawada K, Katsuragi K, Matsuura M, Seno H.

Choledochoduodenal Fistula during Chemotherapy with Brentuximab Vedotin for Methotrexate-associated Lymphoproliferative Disorder.
Intern Med. 2018 Aug 1;57(15):2203-2207.

20. Nakajima A, Vogelzang A, Maruya M, Miyajima M, Murata M, Son A, Kuwahara T, Tsuruyama T, Yamada S, Matsuura M, Nakase H, Peterson DA, Fagarasan S, Suzuki K.

IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria.
J Exp Med. 2018 Aug 6;215(8):2019-2034.

21. Yoshikawa T, Ohana M, Fukuda A.

High Fever After Radiofrequency Ablation of Hepatocellular Carcinoma.
Gastroenterology. 2018 Aug;155(2):e3-e4.

22. Matsumori T, Shiokawa M, Kodama Y.

Pancreatic Mass in a Patient With an Increased Serum Level of IgG4.
Gastroenterology. 2018 Aug;155(2):269-270.

23. Yamashiki N, Yoshizwa A, Ueda Y, Kaido T, Okajima H, Marusawa H, Seno H, Uemoto S.

The use of hepatitis B immunoglobulin with or without hepatitis B vaccine to prevent de novo hepatitis B in pediatric recipients of anti-HBc-positive livers.
Pediatr Transplant. 2018 Aug;22(5):e13227.

24. Kimura Y, Fukuda A, Ogawa S, Maruno T, Takada Y, Tsuda M, Hiramatsu Y, Araki O, Nagao M, Yoshikawa T, Ikuta K, Yoshioka T, Wang Z, Akiyama H, Wright CV, Takaori K, Uemoto S, Chiba T, Seno H.

ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice.
Gastroenterology. 2018 Jul;155(1):194-209.e2

25. Nagao M, Fukuda A, Seno H.

An Unusual Cause of Thickening of the Rectal Wall.
J Gastroenterol Hepatol. 2018 Jul;33(7):1307.

26. Iguchi T, Takaori K, Mii A, Sato Y, Suzuki Y, Yoshifuji H, Seno H, Ogawa O, Omori K, Bessho K, Kondo S, Yoshizaki T, Nakashima H, Saito T, Mimori T, Haga H, Kawano M, Yanagita M.

Glucocorticoid receptor expression in resident and hematopoietic cells in IgG4-related disease.
Mod Pathol. 2018 Jun;31(6):890-899.

27. Eso Y Yoshioka M, Seno H.

Lanthanum phosphate deposition in the gastroduodenal mucosa: An unusual cause of epigastric discomfort.
J Gastroenterol Hepatol. 2018 Jun;33(6):1165.

28. Kubota T, Hata K, Sozu T, Ueda Y, Hirao H, Okamura Y, Tamaki I, Yoshikawa J, Kusakabe J, Tanaka H, Kageyama S, Anazawa T, Yoshizawa A, Yagi S, Yamashiki N, Okajima H, Kaido T, Uemoto S.

Impact of donor age on recipient survival in adult-to-adult living-donor liver transplantation.
Ann Surg. 2018 Jun;267(6):1126-1133.

29. Eso Y, Marusawa H.

Novel approaches for molecular targeted therapy against hepatocellular carcinoma.
Hepatol Res. 2018 Jul;48(8):597-607.

30. Sakuma Y, Kodama Y, Eguchi T, Uza N, Tsuji Y, Shiokawa M, Maruno T, Kuriyama K, Nishikawa Y, Yamauchi Y, Tsuda M, Ueda T, Matsumori T, Morita T, Tomono T, Kakiuchi N, Mima A, Sogabe Y, Marui S, Kuwada T, Okada A, Watanabe T, Nakase H, Chiba T, Seno H.

Chemokine CXCL16 mediates acinar cell necrosis in cerulein induced acute pancreatitis in mice.
Sci Rep. 2018 Jun 11;8(1):8829.

31. Muta Y, Fujita Y, Sumiyama K, Sakurai A, Taketo MM, Chiba T, Seno H, Aoki K, Matsuda M, Imajo M.

Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine.
Nat Commun. 2018 Jun 5;9(1):2174.

32. Araki O, Fukuda A, Kusaka T, Seno H.

A case of ceco-colonic intussusception after the endoscopic submucosal dissection of a cecal adenoma.
Gastrointest Endosc. 2018 Jun;87(6):1589-1590.

33. Sogabe Y, Kodama Y, Honjo H, Aoyama I, Muramoto Y, Koga E, Yanaidani T, Kawai M, Yoshikawa T, Matsumoto S, Matsumoto A, Mori Y, Ono C, Nishida M, Nishida Y, Mikami T, Matsunaga Y, Miyamoto Y, Kitami M, Nishikawa K, Kondo M, Miyake N, Kawanami C, Seno H.

Tumor Invasion to the Arteries Feeding the Gallbladder as a Novel Risk Factor for Cholecystitis after Metallic Stent Placement in Distal Malignant Biliary Obstruction.
Dig Endosc. 2018 May;30(3):380-387.

34. Perron A, Nishikawa Y, Iwata J, Shimojo H, Takaya J, Kobayashi K, Imayoshi I, Mbenza NM, Takenoya M, Kageyama R, Kodama Y, Uesugi M.

Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone.
J Biol Chem. 2018 May 25;293(21):8285-8294.

35. Kanda K, Sakamoto J, Matsumoto Y, Ikuta K, Goto N, Morita Y, Ohno M, Nishi K, Eto K, Kimura Y, Nakanishi Y, Ikegami K, Yoshikawa T, Fukuda A, Kawada K, Sakai Y, Ito A, Yoshida M, Kimura T, Chiba T, Nishi E, Seno H.

Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation.
JCI Insight. 2018 Apr 19;3(8):e91316

36. Kondo T, Kanai M, Kou T, Sakuma T, Mochizuki H, Kamada M, Nakatsui M, Uza N, Kodama Y, Masui T, Takaori K, Matsumoto S, Miyake H, Okuno Y, Muto M.

Association between homologous recombination repair gene mutations and response to oxaliplatin in pancreatic cancer.

Oncotarget. 2018 Apr 13;9(28):19817-19825.

37. Tamaoki M, Komatsuzaki R, Komatsu M, Minashi K, Aoyagi K, Nishimura T, Chiwaki F, Hiroki T, Daiko H, Morishita K, Sakai Y, Seno H, Chiba T, Muto M, Yoshida T, Sasaki H.

Multiple roles of SIM2 in esophageal squamous cell carcinoma and its clinical implications.
Cancer Sci. 2018 Apr;109(4):1121-1134.

38. Shelton PM, Duran A, Nakanishi Y, Reina-Campos M, Kasashima H, Llado V, Ma L, Campos A, Garcia-Olmo D, Garcia-Arranz M, Garcia-Olmo DC, Olmedillas-Lopez S, Caceres JF, Diaz-Meco MT, Moscat J.

The Secretion of miR-200s by a PKCζ/ADAR2 Signaling Axis Promotes Liver Metastasis in Colorectal Cancer.
Cell Rep. 2018 Apr 24;23(4):1178-1191.

39. Matsumoto T, Seno H.

Updated Trends in Gallbladder and Other Biliary Tract Cancers Worldwide.
Clin Gastroenterol Hepatol. 2018 Mar;16(3):339-340.

40. Nagao M, Fukuda S, Matsumura T, Kimura T, Seno H.

Pulmonary Actinomycosis Mimicking a Lung Metastasis from Esophageal Cancer; A Case Report.
BMC Pulm Med. 2018 Feb 27;18(1):39.

41. Eso Y, Yoshiji S, Nakakubo Y, Matsuura M, Seno H.

Acute anorectal thrombophlebitis caused by a protein C deficiency.
Intern Med. 2018 Jan 15;57(2):209-212.

42. Notohara K, Kamisawa T, Uchida K, Zen Y, Kawano M, Kasashima S, Sato Y,Shiokawa M, Uehara T, Yoshifuji H, Hayashi H, Inoue K, Iwasaki K, Kawano H,Matsubayashi H, Moritani Y, Murakawa K, Oka Y, Tateno M, Okazaki K, Chiba T.

Gastrointestinal manifestation of immunoglobulin G4-related disease:clarification through a multicenter survey.
J Gastroenterol. 2018 Jul;53(7):845-853.

43. Yamamoto S, Yamada M, Matsumura K.

Mimicking small intestinal anisakiasis.
Gastroenterology, 2018 May;154(6):e9-e10.